What does Vgpr mean?
Partial response (PR) PR is a less favorable response to treatment than stringent complete response (sCR), complete response (CR), or very good partial response (VGPR) but is better than stable disease (SD).
What is VRD chemotherapy?
RVd (Revlimid® + Velcade® + dexamethasone) is a Chemotherapy Regimen for Multiple Myeloma (MM) Click the orange links and we’ll show you extra information. Click this one to give it a try. How does RVd work? Each of the medications in the RVd regimen is designed to kill or slow the growth of myeloma cells.
What is a complete response in myeloma?
Definition of complete response. When HDT was introduced in the treatment of MM, CR was first defined as the disappearance of the M-component on serum and/or urine electrophoresis with 5% or fewer plasma cells on bone marrow aspiration.
What are the stages of multiple myeloma?
Multiple myeloma stages and types
- Durie-Salmon Staging. In this system, there are three stages of myeloma: Stage I, Stage II, and Stage III.
- International Staging System (ISS)
- Monoclonal Gammopathy of Undetermined Significance (MGUS)
- Asymptomatic (smoldering/indolent) myeloma.
- Symptomatic (active) myeloma.
What is progressive myeloma?
Multiple myeloma (MM) is a malignant, progressive plasma cell tumor characterized by overproduction of monoclonal immunoglobulins, osteolytic bone lesions, renal disease, and immunodeficiency.
What is VRD regimen for multiple myeloma?
The addition of daratumumab (Darzalex) to the carfilzomib (Kyprolis), lenalidomide (Revlimid), and dexamethasone (KRd) regimen led to strong responses in patients with newly diagnosed multiple myeloma, including minimal residual disease (MRD) negativity in nearly three-quarters of the population, according to new …
Is stem cell transplant necessary for multiple myeloma?
Nevertheless, stem cell transplants remain an important part of multiple myeloma treatment for eligible individuals. Research has found that having an autologous stem cell transplant can improve overall survival by a median of 12 months .