Can Bombay blood group donate blood?
For this reason people who have Bombay phenotype can donate red blood cells to any member of the ABO blood group system (unless some other blood factor gene, such as Rh, is incompatible), but they cannot receive blood from any member of the ABO blood group system (which always contains one or more of A, B or H antigens …
What is H antigen blood type?
Also known as substance H, H antigen is a precursor to each of the ABO blood group antigens, apparently present in all people except those with the Bombay Blood phenotype (see hh blood group) Histocompatibility antigen, a major factor in graft rejection.
What is anti-H antibody?
Anti-H antibody is a type of anti-red blood cell (RBC) antibody that agglutinates with H antigen, which is universally present on human RBCs. The most widely known problem related to the anti-H antibody is the potentially lethal hemolytic transfusion reaction seen in individuals with the Bombay O blood type [1,2,3].
How do I know if I have Bombay blood type?
The Bombay phenotype is characterized by the absence of A, B, and H antigens on its red cells and the serum of these individuals have anti-A and anti-B . But the serum that agglutinates red cells of ‘O’ group individuals through a wide thermal range may be due to presence of strongly reactive anti-H antibodies .
What is Bombay O positive blood?
Abstract. The Bombay blood group is a rare blood group, phenotypes of this group lacking H antigen on the red cell membrane and have anti-H in the serum. It fails to express any A, B or H antigen on their red cells or other tissues. The existence of a human H/h genetic polymorphism was first established by Bhende et al …
What is H antigen in Bombay blood?
The Bombay blood group, also called hh, is deficient in expressing antigen H, meaning the RBC has no antigen H. For instance, in the AB blood group, both antigens A and B are found. A will have A antigens; B will have B antigens. In hh, there are no A or B antigens.
How do you get anti-H?
The rare Bombay phenotype (group Oh; and phenotypically O on serologic testing) results from homozygosity for inactive H(FUT1) and Se(FUT2). Bombay individuals lack the H antigen on RBCs, tissues, and secretions, and make a potent anti-H. These individuals must be transfused with RBCs from other Bombay individuals.
What does the H antigen do?
The Hh blood group contains one antigen, the H antigen, which is found on virtually all RBCs and is the building block for the production of the antigens within the ABO blood group.
Which blood group is universal donor?
blood group type O negative blood
For emergency transfusions, blood group type O negative blood is the variety of blood that has the lowest risk of causing serious reactions for most people who receive it. Because of this, it’s sometimes called the universal blood donor type.
What is the difference between blood group O and Bombay?
What is the Difference Between Bombay Blood Group and O Blood Group. The main difference between Bombay blood group and O blood group is that the Bombay blood group lacks H antigen in their red blood cells whereas O blood group contains the highest amount of H antigens among all blood phenotypes.