What is the difference between a diuretic and a loop diuretic?
Dilutional hyponatremia is an important complication of treatment with diuretics. An efficacious treatment of that condition seems to be a combination of loop-diuretics and ACE-inhibitors. Thiazides decrease the urinary excretion of calcium, while loop-diuretics have the opposite effect.
What is the difference between a loop diuretic and a potassium sparing diuretic?
When used on their own, potassium-sparing diuretics are weak diuretics. Loop diuretics and thiazide diuretics are stronger than potassium-sparing diuretics with regard to making the kidneys pass out more fluid. However, they also increase the amount of potassium passed out of the body through the kidneys.
What is the difference between loop diuretics and thiazide diuretics?
They may also be used with antihypertensive drugs to control high blood pressure (hypertension). Lasix is an anthranilic acid derivative that is a type of loop diuretic while thiazides are another class of diuretic. A difference is that loop diuretics are more potent than thiazides.
What is the difference between chlorothiazide and hydrochlorothiazide?
Chlorthalidone produces slightly greater reductions in blood pressure compared with hydrochlorothiazide (HCTZ), but it is associated with greater declines in serum potassium levels.
What is the difference between thiazide and thiazide-like diuretics?
A thiazide-like diuretic is a sulfonamide diuretic that has similar physiological properties to a thiazide diuretic, but does not have the chemical properties of a thiazide, lacking the benzothiadiazine molecular structure. Examples include metolazone and chlorthalidone.
When are loop diuretics used?
Loop diuretics are medications used in the management and treatment of fluid overload conditions such as heart failure, nephrotic syndrome or cirrhosis, and hypertension, in addition to edema.
What are loop diuretics examples?
Examples of loop diuretics include:
- Bumetanide (Bumex)
- Ethacrynic acid (Edecrin)
- Furosemide (Lasix)
- Torsemide (Soaanz)
Is chlorothiazide and chlorthalidone the same?
All thiazides have a similar dual-ring structure. Figure 1. Structures of chlorothiazide, HCTZ, and chlorthalidone. Though commonly considered a thiazide, chlorthalidone is not a benzothiadiazine and is more appropriately called a thiazide-like diuretic.
Why is it called a loop diuretic?
A loop diuretic gets its name because it interacts with a structure in the kidney known as the “thick ascending limb of the Loop of Henle.” Loop diuretics prevent absorption of sodium and chloride, which increase the overall amount of sodium and chloride that get excreted in the urine, and the amount of water as well.
What is the bioavailability of LoopLoop diuretics?
Loop diuretics, especially furosemide, are widely used in various conditions. The bioavailability of furosemide differs between oral and intravenous therapy. The threshold and ceiling doses of furosemide differ according to the clinical condition.
What is the difference between all the types of diuretics?
What Is the Difference in Diuretics? 1 Thiazide Diuretics. Medications in this category including hydrochlorothiazide (Microzide) (which is the 11th most prescribed drug in the United States ), chlorthalidone , metolazone , and indapamide. 2 Loop Diuretics. 3 Potassium-Sparing Diuretics. 4 Other Diuretics.
Are loop diuretics effective in advanced CKD patients?
Therefore, furosemide doses lower than 80mg are not effective in advanced CKD patients. Loop diuretics have a ceiling dose; this is the dose that shows the maximum fractional sodium excretion. Although loop diuretics display dose-response curves, doses above the ceiling dose are only moderately effective.