What is cinacalcet good for?

What is cinacalcet good for?

Cinacalcet is used to treat hyperparathyroidism in patients with chronic kidney disease who are on dialysis. Hyperparathyroidism is a condition that is caused when the parathyroid glands located in the neck make too much parathyroid hormone (PTH).

What are the side effects of cinacalcet?

Common side effects of Sensipar include:

  • nausea,
  • vomiting,
  • diarrhea,
  • loss of appetite,
  • muscle pain,
  • mild chest pain,
  • dizziness, or.
  • weakness.

Does Sensipar cause weight gain?

Sensipar side effects muscle pain, tightness, or contraction; a seizure (convulsions); shortness of breath (even with mild exertion), swelling, rapid weight gain; signs of stomach bleeding – bloody or tarry stools, coughing up blood or vomit that looks like coffee grounds; or.

Is cinacalcet FDA approved?

(Nasdaq: AMGN), the world’s largest biotechnology company, today announced that the U.S. Food and Drug Administration (FDA) approved Sensipar (cinacalcet HCl) following a priority review.

Can cinacalcet cause heart palpitations?

allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue. depressed mood. signs and symptoms of a dangerous change in heartbeat or heart rhythm like chest pain; dizziness; fast or irregular heartbeat; palpitations; feeling faint or lightheaded, falls; breathing problems.

Does cinacalcet get dialyzed?

Conclusion: The degree of renal impairment and mode of dialysis do not affect the pharmacokinetics or pharmacodynamics of cinacalcet. Therefore, the dose of cinacalcet does not need to be altered for degree of renal impairment or dialysis modality.

Should you take vitamin D if you have hyperparathyroidism?

Conclusion: Vitamin D deficiency exacerbates primary hyperparathyroidism and vice versa. With care, vitamin D supplementation can safely be given to selected patients with asymptomatic primary hyperparathyroidism and is suggested before deciding on medical or surgical management.

Can Sensipar be cut in half?

Sensipar® is taken once a day in one of the 5 recommended daily doses. Sensipar® tablets should be taken whole. Do not crush or split the tablet.

How long does Sensipar stay in your system?

In phase I-II studies, the maximum effect of cinacalcet was achieved within 2–6 hours after administration, with a terminal half-life of 30–40 hours (30, 31).

When should I take cinacalcet?

It is usually taken once a day with food or shortly after a meal. To help you remember to take cinacalcet, take it at around the same time every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand.

Can you just stop taking cinacalcet?

Cinacalcet may help control your condition but will not cure it. Continue to take cinacalcet even if you feel well. Do not stop taking cinacalcet without talking to your doctor.