What does alternative RNA splicing do?
Alternative splicing is the process that selectively removes introns or exons, or parts thereof, to generate multiple messenger RNAs (mRNAs) from a single precursor mRNA (pre-mRNA) (2). First reported in 1980, RNA alternative splicing events have been found in the majority of eukaryotic genes.
What is the purpose of alternative splicing quizlet?
In alternative splicing, different combinations of exons from the same gene are combined to result in different protein products. Often, these different splice variants are expressed in different tissues. This allows for an increased diversity of proteins to be produced.
What is RNA splicing quizlet?
RNA splicing. The process of intron removal that converts the pre-mRNA into mature mRNA. It must occur with precision to avoid the loss of even a single nucleotide at the sites where exons are joined.
Which of the following correctly describes alternative splicing?
Which of the following processes correctly describes alternative RNA splicing? It can allow the production of proteins of different sizes and functions from a single mRNA. In bacteria, there are 61 mRNA codons that specify an amino acid, but only 45 tRNAs.
Why is alternative splicing beneficial?
Alternative splicing affords a significant evolutionary advantage by providing a large source of proteomic diversity. Alternative splicing is often regulated at the tissue level, and tissue-specific variants cooperate to modulate protein–protein interaction networks.
Why is alternative splicing of mRNA in eukaryotic cells important quizlet?
A single transcript with multiple introns may be spliced in different ways to generate different mRNAs and different protein products with different functions. Thus, this alternative splicing is one more layer contributing to the diversity of the genetic information stored in DNA.
What is the result of alternative splicing of mRNA quizlet?
What is the result of alternative splicing of mRNA? Isoenzymes are produced from a single gene.
What happens during splicing quizlet?
RNA splicing – The process of excising introns from RNA and connecting the exons into a continuous mRNA. Occurs during and/or after transcription. Splicing requires the 5′ and 3′ splice sites and a branch site just upstream of the 3′ splice site.
What regulates alternative splicing?
Splicing is regulated by trans-acting proteins (repressors and activators) and corresponding cis-acting regulatory sites (silencers and enhancers) on the pre-mRNA. However, as part of the complexity of alternative splicing, it is noted that the effects of a splicing factor are frequently position-dependent.
What is the purpose of alternative splicing in eukaryotic cells quizlet?
What is the purpose of alternative splicing in eukaryotic cells? Produce multiple polypeptide sequences from a single primary transcript.