What are the causes of hypogonadotropic hypogonadism?

What are the causes of hypogonadotropic hypogonadism?

There are several causes of HH:

  • Damage to the pituitary gland or hypothalamus from surgery, injury, tumor, infection, or radiation.
  • Genetic defects.
  • High doses or long-term use of opioid or steroid (glucocorticoid) medicines.
  • High prolactin level (a hormone released by the pituitary)
  • Severe stress.

What is the treatment for hypogonadotropic hypogonadism?

Male hypogonadotropic hypogonadism (MHH), a disorder associated with infertility, is treated with testosterone replacement therapy (TRT) and/or gonadotropins replacement therapy (GRT) (TRT and GRT, together with HRT hormone replacement therapy).

How common is hypogonadotropic hypogonadism?

The incidence of congenital hypogonadotropic hypogonadism is approximately 1-10:100,000 live births, and approximately 2/3 and 1/3 of cases are caused by Kallmann syndrome (KS) and idiopathic hypogonadotropic hypogonadism, respectively.

What is Normogonadotropic hypogonadism?

The term normogonadotropic hypogonadism denotes symptoms or signs of hypogonadism together with low serum T and normal LH levels.

What is the difference between hypogonadotropic hypogonadism and hypogonadism?

Hypogonadism is a condition in which the male testes or the female ovaries produce little or no sex hormones. Hypogonadotropic hypogonadism (HH) is a form of hypogonadism that is due to a problem with the pituitary gland or hypothalamus.

Is hypogonadotropic hypogonadism reversible?

Congenital hypogonadotropic hypogonadism (CHH) is characterized by lack of puberty and infertility. Traditionally, it has been considered a life-long condition yet cases of reversibility have been described wherein patients spontaneously recover function of the reproductive axis following treatment.

Can you get pregnant with hypogonadotropic hypogonadism?

In aged hypogonadotropic hypogonadism patients, a pregnancy rate of 50% was achieved. Conclusion. Hypogonadotropic hypogonadism women undergoing in vitro fertilization were found to be good responders. In the presence of advanced age, management of these patients becomes challenging.

What is hypogonadotropic amenorrhea?

HYPOGONADOTROPIC HYPOGONADISM Hypothalamic amenorrhea is associated with abnormalities in gonadotropin-releasing hormone (GnRH) secretion and disruption of the hypothalamic-pituitary-ovarian axis. The condition often is caused by excessive weight loss, exercise, or stress.

What are symptoms of low FSH?

FSH and LH deficiency: In women, symptoms include irregular or stopped menstrual periods and infertility. In men, symptoms include loss of body and facial hair, weakness, lack of interest in sexual activity, erectile dysfunction, and infertility.