Is Langerhans cell histiocytosis cancer?
Langerhans cell histiocytosis (LCH) LCH is classified as a cancer and sometimes requires treatment with chemotherapy. LCH patients are therefore usually treated by children’s cancer specialists (paediatric oncologists/ haematologists).
Is Langerhans cell histiocytosis a type of lymphoma?
In a small subset of patients, LCH has been identified as an incidental finding in biopsy specimens involved by lymphoma. Classical Hodgkin lymphoma is the most common associated lymphoma,23–26 whereas only sporadic cases of other types of non-Hodgkin lymphoma associated with LCH are reported in the literature.
Is LCH fatal?
Is LCH fatal? It can be. A small percentage of patients, most often those with multisystem risk-organ involvement that is unresponsive to treatment, may not survive.
What are the symptoms of histiocytosis?
The first sign of histiocytosis is often a rash on the scalp, similar to cradle cap. There may be a pain in a bone, discharge from the ear, loss of appetite and fever. Sometimes the stomach is swollen and painful.
How do you test for LCH?
Testing for Langerhans cell histiocytosis (LCH) may include bronchoscopy with biopsy , x-ray , skin biopsy, bone marrow biopsy, complete blood count, skeletal X-rays survey, pulmonary function tests and liver funcion tests, as well as MRI and CT scanning of the head to evaluate possible abnormalities of the …
Is LCH a solid tumor?
Langerhans cell histiocytosis (LCH) is a rare disorder of histiocyte proliferation. Previous case studies suggest a higher prevalence of hematologic and solid malignancies among LCH patients, possibly due to treatment with tumorigenic agents such as etoposide.
Is there a cure for histiocytosis?
Sometimes histiocytosis involves only one area of the body. This may be a particular bone, for example. In these cases, removing the tumor is the only treatment needed. In other cases, removing a part of a tumor that is pressing on an important area, such as behind the eye, can improve symptoms.
Does histiocytosis go away?
In many people with Langerhans cell histiocytosis, the disorder eventually goes away with appropriate treatment. It may even disappear on its own, especially if the disease occurs only in the skin.