How does polio cause hypertension?
20, 1952.) hypertension. Salus reporting on three cases of hypertension associated with poliomyelitis, considered the inflammatory changes in the brain stem, especially in the region of formatio reticularis, to be an important factor in producing hypertension.
What is the pathophysiology of post-polio syndrome?
The cause of post-polio syndrome is not known at this time. One theory is that it may be related to the recovery from the original polio. During recovery from polio, nerve cells in affected muscles may regrow many smaller branches (dendrites) from the message-transmitting large branches (axons) of nerve cells.
Does post-polio syndrome affect the heart?
patients with post-polio syndrome Neuromuscular diseases (NMDs) can affect anyone at any time. They cause muscle weakness that can affect the heart, breathing, coughing, swallowing, speech, and limbs muscles, all of which cause disability and compromise the quality of life.
Does polio affect blood pressure?
Previous studies on cardiovascular risk factors in the post-polio syndrome have found a higher prevalence of hypertension, ischemic heart disease, hyperlipidaemia, and stroke in these patients.
Does polio affect the circulatory system?
Polio survivors with respiratory difficulties may develop hypoxemia (low levels of oxygen). Any of these circum- stances – deconditioning, obesity, dyslipidemia , and hy poxemia – can increase the risk for cardio- vascular disease.
What is Post-polio?
Post-polio syndrome (PPS) is a condition that can affect polio survivors decades after they recover from their initial poliovirus infection. Unlike poliovirus, PPS is not contagious.
How does poliovirus cause paralysis?
With the destruction of nerve cells, the muscles no longer receive signals from the brain or spinal cord; without nerve stimulation, the muscles atrophy, becoming weak, floppy and poorly controlled, and finally completely paralyzed.
Is post-polio syndrome a neurological condition?
Post-polio syndrome (PPS) is a neurological condition that affects polio survivors decades after their initial infection.
Is post-polio syndrome an autoimmune disease?
An inflammatory or autoimmune basis to post-polio syndrome has also been proposed. This hypothesis originates from post mortem observations of inflammatory changes in the spinal cord of PPS patients (35, 36). The role of inflammation is also supported by in vivo evidence.
Is post-polio a motor neuron disease?
Post-polio syndrome is a motor neuron disease that oc- curs in 15%-80% of patients with a history of polio.